Albumin-Folate Conjugates for Drug-targeting in Photodynamic Therapy
نویسندگان
چکیده
منابع مشابه
Antibody Drug Conjugates for Cancer Therapy
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Photodynamic therapy (PDT) is an emerging theranostic modality for various cancers and diseases. The focus of this study was the development of tumor-targeting albumin nanoparticles containing photosensitizers for efficient PDT. To produce tumor-targeting albumin nanoparticles, the hydrophobic photosensitizer, chlorin e6 (Ce6), was chemically conjugated to human serum albumin (HSA). The conjuga...
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Tumor-targeted imaging and therapy have been the challenging issue in the clinical field. Herein, we report tumor-targeting hyaluronic acid nanoparticles (HANPs) as the carrier of the hydrophobic photosensitizer, chlorin e6 (Ce6) for simultaneous photodynamic imaging and therapy. First, self-assembled HANPs were synthesized by chemical conjugation of aminated 5β-cholanic acid, polyethylene glyc...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 2016
ISSN: 0031-8655
DOI: 10.1111/php.12602